mouse EIF3G shRNA silencing AAV

Cat. No: shAAV-258211

Availability: 4-5 weeks

Name: AAV-m-EIF3G-shRNA

This is an AAV expressing shRNA for silencing of Mouse Eif3g.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Eif3g
Gene Name: eukaryotic translation initiation factor 3, subunit G
Gene ID: 53356
Gene Synonyms: 44kDa; D0Jmb4; eIF3-p44; Eif3s4; p44; TU-189B2
ORF Size: 963 bp
RefSeq#: NM_016876
Gene Description: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit can bind 18S rRNA.
UniGene ID: Mm.427309