human DBH shRNA silencing AAV

Cat. No: shAAV-206620

Availability: 6-8 weeks

Name: AAV-h-DBH-shRNA

This is an AAV expressing shRNA for silencing of Human DBH.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: DBH
Gene Name: dopamine beta-hydroxylase
Gene ID: 1621
Gene Synonyms: DBM
ORF Size: 1812 bp
RefSeq#: NM_000787
Gene Description: DBH is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. It is present in the synaptic vesicles of postganglionic sympathetic neurons and converts dopamine to norepinephrine. It exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide.
UniGene ID: Hs.591890
HGNC ID: HGNC:2689