human BID shRNA silencing AAV

Cat. No: shAAV-202137

Availability: 4-5 weeks

Name: AAV-h-BID-shRNA

This is an AAV expressing shRNA for silencing of Human BID.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: BID
Gene Name: BH3 interacting domain death agonist
Gene ID: 637
Gene Synonyms: FP497
ORF Size: 588 bp
RefSeq#: NM_001196
Gene Description: BID encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
UniGene ID: Hs.591054
HGNC ID: HGNC:1050