mouse PHC2 shRNA silencing AAV

Cat. No: shAAV-268516

Availability: 4-5 weeks

Name: AAV-m-PHC2-shRNA

This is an AAV expressing shRNA for silencing of Mouse Phc2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Phc2
Gene Name: polyhomeotic-like 2 (Drosophila)
Gene ID: 54383
Gene Synonyms: A3galt2; AA415044; D130050K19Rik; D4Ertd810e; Edr2; Mph2; p36
ORF Size: 2553 bp
RefSeq#: NM_018774
Gene Description: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
UniGene ID: Mm.477746