human BTN3A1 shRNA silencing AAV

Cat. No: shAAV-202344

Availability: 6-8 weeks

Name: AAV-h-BTN3A1-shRNA

This is an AAV expressing shRNA for silencing of Human BTN3A1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: BTN3A1
Gene Name: butyrophilin subfamily 3 member A1
Gene ID: 11119
Gene Synonyms: BT3.1; BTF5; BTN3.1; CD277
ORF Size: 1542 bp
RefSeq#: NM_007048
Gene Description: The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A1) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 (PubMed 20208008)).(supplied by OMIM, Nov 2010)
UniGene ID: Hs.191510
HGNC ID: HGNC:1138