mouse ATF6 shRNA silencing AAV

Cat. No: shAAV-253211

Availability: 4-5 weeks

Name: AAV-m-ATF6-shRNA

This is an AAV expressing shRNA for silencing of Mouse Atf6.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Atf6
Gene Name: activating transcription factor 6
Gene ID: 226641
Gene Synonyms: 9130025P16Rik; 9630036G24; AA789574; Atf6alpha; ESTM49
ORF Size: 1971 bp
RefSeq#: NM_001081304
Gene Description: Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N(9)-CCAC[GA]-3') and of ERSE II (5'-ATTGG-N-CCACG-3'). Binding to ERSE requires binding of NF-Y to ERSE. Could also be involved in activation of transcription by the serum response factor.
UniGene ID: Mm.377046