human STAMBP shRNA silencing AAV

Cat. No: shAAV-224506

Availability: 4-5 weeks

Name: AAV-h-STAMBP-shRNA

This is an AAV expressing shRNA for silencing of Human STAMBP.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: STAMBP
Gene Name: STAM binding protein
Gene ID: 10617
Gene Synonyms: AMSH; MICCAP
ORF Size: 1275 bp
RefSeq#: NM_006463
Gene Description: Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
UniGene ID: Hs.657598
HGNC ID: HGNC:16950