human BTK shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

BTK

Gene Name

Bruton tyrosine kinase

Gene ID

695

Gene Synonyms

AGMX1; AT; ATK; BPK; IMD1; PSCTK1; XLA

ORF Size

1980 bp

RefSeq#

NM_000061

Gene Description

BTK plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement.

UniGene ID

Hs.159494

HGNC ID

HGNC:1133