human LDHB shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

LDHB

Gene Name

lactate dehydrogenase B

Gene ID

3945

Gene Synonyms

HEL-S-281; LDH-B; LDH-H; LDHBD; TRG-5

ORF Size

1005 bp

RefSeq#

NM_002300

Gene Description

LDHB encodes an enzyme which catalyzes the reversible conversion of lactate and pyruvate, and NAD and NADH, in the glycolytic pathway. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on the X chromosome and on chromosome. Multiple alternatively spliced variants, encoding the same protein, have been identified.

UniGene ID

Hs.446149

HGNC ID

HGNC:6541