human CPT1A shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-205937
Availability:
3-5 weeks
Name:
Ad-h-CPT1A-shRNA
This is an Adenovirus expressing shRNA for silencing of Human CPT1A.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- CPT1A
- Gene Name
- carnitine palmitoyltransferase 1A
- Gene ID
- 1374
- Gene Synonyms
- CPT1; CPT1-L; L-CPT1
- ORF Size
- 2271 bp
- RefSeq#
- NM_001876
- Gene Description
- The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- UniGene ID
- Hs.503043
- HGNC ID
- HGNC:2328
Related Products
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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