human FOSB shRNA silencing Adenovirus

Product Info

Knockdown

>50% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

FOSB

Gene Name

FosB proto-oncogene, AP-1 transcription factor subunit

Gene ID

2354

Gene Synonyms

AP-1; G0S3; GOS3; GOSB

ORF Size

1017 bp

RefSeq#

NM_006732

Gene Description

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UniGene ID

Hs.590958

HGNC ID

HGNC:3797