human FYN shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

FYN

Gene Name

FYN proto-oncogene, Src family tyrosine kinase

Gene ID

2534

Gene Synonyms

p59-FYN; SLK; SYN

ORF Size

1449 bp

RefSeq#

NM_002037

Gene Description

FYN is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.

UniGene ID

Hs.390567

HGNC ID

HGNC:4037