human GCNT1 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

GCNT1

Gene Name

glucosaminyl (N-acetyl) transferase 1, core 2

Gene ID

2650

Gene Synonyms

C2GNT; C2GNT-L; C2GNT1; G6NT; NACGT2; NAGCT2

ORF Size

1287 bp

RefSeq#

NM_001490

Gene Description

GCNT1 is a member of the beta-1,6-N-acetylglucosaminyltransferase gene family. It is essential to the formation of Gal beta 1-3(GlcNAc beta 1-6)GalNAc structures and the core 2 O-glycan branch. The gene coding this enzyme was originally mapped to 9q21, but was later localized to 9q13. Multiple alternatively spliced variants, encoding the same protein, have been identified.

UniGene ID

Hs.521568

HGNC ID

HGNC:4203