human EPHA3 shRNA silencing AAV

Cat. No: shAAV-207980

Availability: 4-5 weeks

Name: AAV-h-EPHA3-shRNA

This is an AAV expressing shRNA for silencing of Human EPHA3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: EPHA3
Gene Name: EPH receptor A3
Gene ID: 2042
Gene Synonyms: EK4; ETK; ETK1; HEK; HEK4; TYRO4
ORF Size: 2952 bp
RefSeq#: NM_005233
Gene Description: EPHA3 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene.
UniGene ID: Hs.123642
HGNC ID: HGNC:3387