human POLE3 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

POLE3

Gene Name

DNA polymerase epsilon 3, accessory subunit

Gene ID

54107

Gene Synonyms

CHARAC17; CHRAC17; p17; YBL1

ORF Size

444 bp

RefSeq#

NM_017443

Gene Description

POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.(supplied by OMIM, Apr 2004)

UniGene ID

Hs.108112

HGNC ID

HGNC:13546