human SUMO3 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

SUMO3

Gene Name

small ubiquitin-like modifier 3

Gene ID

6612

Gene Synonyms

SMT3A; Smt3B; SMT3H1; SUMO-3

ORF Size

312 bp

RefSeq#

NM_006936

Gene Description

SUMO proteins, such as SUMO3, and ubiquitin (see MIM 191339) posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability (Su and Li, 2002 (PubMed 12383504)).(supplied by OMIM, Mar 2008)

UniGene ID

Hs.474005

HGNC ID

HGNC:11124