human GPAM shRNA silencing Adenovirus

Product Info

Knockdown

>70% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

GPAM

Gene Name

glycerol-3-phosphate acyltransferase, mitochondrial

Gene ID

57678

Gene Synonyms

GPAT; GPAT1

ORF Size

2487 bp

RefSeq#

NM_020918

Gene Description

GPAM encodes a mitochondrial enzyme which prefers saturated fatty acids as its substrate for the synthesis of glycerolipids. This metabolic pathway's first step is catalyzed by the encoded enzyme. Two forms for this enzyme exist, one in the mitochondria and one in the endoplasmic reticulum. Two alternatively spliced transcript variants have been described for this gene.

UniGene ID

Hs.42586

HGNC ID

HGNC:24865