human ATG12 shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

ATG12

Gene Name

autophagy related 12

Gene ID

9140

Gene Synonyms

APG12; APG12L; FBR93; HAPG12

ORF Size

564 bp

RefSeq#

NM_004707

Gene Description

Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 (PubMed 9852036)).(supplied by OMIM, Mar 2008)

UniGene ID

Hs.264482

HGNC ID

HGNC:588