human SLC30A10 shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

SLC30A10

Gene Name

solute carrier family 30 member 10

Gene ID

55532

Gene Synonyms

HMDPC; HMNDYT1; ZnT-10; ZNT10; ZNT8; ZRC1

ORF Size

1455 bp

RefSeq#

NM_018713

Gene Description

SLC30A10 is highly expressed in the liver and is inducible by manganese. Its protein product appears to be critical in maintaining manganese levels, and has higher specificity for manganese than zinc. Loss of function mutations appear to result in a pleomorphic phenotype, including dystonia and adult-onset parkinsonism. Alternatively spliced transcript variants have been observed for this gene.

UniGene ID

Hs.679909

HGNC ID

HGNC:25355