human EDNRA shRNA silencing AAV

Cat. No: shAAV-207569

Availability: 4-5 weeks

Name: AAV-h-EDNRA-shRNA

This is an AAV expressing shRNA for silencing of Human EDNRA.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: EDNRA
Gene Name: endothelin receptor type A
Gene ID: 1909
Gene Synonyms: ET-A; ETA; ETA-R; ETAR; ETRA; hET-AR; MFDA
ORF Size: 1284 bp
RefSeq#: NM_001957
Gene Description: EDNRA encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants.
UniGene ID: Hs.183713
HGNC ID: HGNC:3179