human OPRM1 shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

OPRM1

Gene Name

opioid receptor mu 1

Gene ID

4988

Gene Synonyms

LMOR; M-OR-1; MOP; MOR; MOR1; OPRM

ORF Size

1203 bp

RefSeq#

NM_000914

Gene Description

OPRM1 encodes one of three opioid receptors. The mu opioid receptor is the principal target of endogenous opioid peptides and opioid analgesic agents such a s beta-endorphn and enkephalins. The NM_001008503.1:c.118A>G allele had been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene.

UniGene ID

Hs.2353

HGNC ID

HGNC:8156