human PPP1R15A shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

PPP1R15A

Gene Name

protein phosphatase 1 regulatory subunit 15A

Gene ID

23645

Gene Synonyms

GADD34

ORF Size

2025 bp

RefSeq#

NM_014330

Gene Description

PPP1R15A is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation.

UniGene ID

Hs.631593

HGNC ID

HGNC:14375