human MAD1L1 shRNA silencing Adenovirus

Product Info

Knockdown

>60% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

MAD1L1

Gene Name

MAD1 mitotic arrest deficient like 1

Gene ID

8379

Gene Synonyms

MAD1; PIG9; TP53I9; TXBP181

ORF Size

2157 bp

RefSeq#

NM_003550

Gene Description

MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene.

UniGene ID

Hs.654838

HGNC ID

HGNC:6762