human TRAP1 shRNA silencing AAV

Cat. No: shAAV-226346

Availability: 4-5 weeks

Name: AAV-h-TRAP1-shRNA

This is an AAV expressing shRNA for silencing of Human TRAP1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TRAP1
Gene Name: TNF receptor associated protein 1
Gene ID: 10131
Gene Synonyms: HSP 75; HSP75; HSP90L; TRAP-1
ORF Size: 2115 bp
RefSeq#: NM_016292
Gene Description: HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. TRAP1 is a mitochondrial HSP90 protein. Other HSP90 proteins are found in cytosol (see HSP90AA1; MIM 140571) and endoplasmic reticulum (HSP90B1; MIM 191175) (Chen et al., 2005 (PubMed 16269234)).(supplied by OMIM, Aug 2008)
UniGene ID: Hs.30345
HGNC ID: HGNC:16264