human SFRP2 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

SFRP2

Gene Name

secreted frizzled related protein 2

Gene ID

6423

Gene Synonyms

FRP-2; SARP1; SDF-5

ORF Size

888 bp

RefSeq#

NM_003013

Gene Description

SFRP2 encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer.

UniGene ID

Hs.481022

HGNC ID

HGNC:10777