human ATG9B shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

ATG9B

Gene Name

ATG9 autophagy related 9 homolog B (S. cerevisiae)

Gene ID

285973

Gene Synonyms

APG9L2; NOS3AS; SONE;

ORF Size

1233 bp

RefSeq#

NM_173681

Gene Description

ATG9B functions in the regulation of autophagy, a lysosomal degradation pathway. ATG9B also functions as the antisense to and in the posttranscriptional regulation of endothelial nitric oxide synthase 3. Mutations in this gene and disruption of the autophagy process have been associated with multiple cancers. Transcript evidence indicates this is a nonsense-mediated decay (NMD) candidate; however, published reports support a valid protein.

UniGene ID

Hs.707300

HGNC ID

HGNC:21899