human FLT4 shRNA silencing Adenovirus

Product Info

Knockdown

>70% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

FLT4

Gene Name

fms related tyrosine kinase 4

Gene ID

2324

Gene Synonyms

FLT-4; FLT41; LMPH1A; PCL; VEGFR-3; VEGFR3

ORF Size

4092 bp

RefSeq#

NM_002020

Gene Description

FLT4 encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA.

UniGene ID

Hs.646917

HGNC ID

HGNC:3767