human ZFP36L1 shRNA silencing Adenovirus

Product Info

Knockdown

>70% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

ZFP36L1

Gene Name

ZFP36 ring finger protein like 1

Gene ID

677

Gene Synonyms

Berg36; BRF1; cMG1; ERF-1; ERF1; RNF162B; TIS11B

ORF Size

1017 bp

RefSeq#

NM_004926

Gene Description

ZFP36L1 is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. ZFP36L1 is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UniGene ID

Hs.707091

HGNC ID

HGNC:1107