human CISD1 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

CISD1

Gene Name

CDGSH iron sulfur domain 1

Gene ID

55847

Gene Synonyms

C10orf70; MDS029; mitoNEET; ZCD1

ORF Size

327 bp

RefSeq#

NM_018464

Gene Description

CISD1 encodes a protein with a CDGSH iron-sulfur domain and has been shown to bind a redox-active (2Fe-2S) cluster. The encoded protein has been localized to the outer membrane of mitochondria and is thought to play a role in regulation of oxidation. Genes encoding similar proteins are located on chromosomes 4 and 17, and a pseudogene of this gene is located on chromosome 2.

UniGene ID

Hs.370102

HGNC ID

HGNC:30880