human FOXO3 shRNA silencing Adenovirus

Product Info

Knockdown

>50% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

FOXO3

Gene Name

forkhead box O3

Gene ID

2309

Gene Synonyms

AF6q21; FKHRL1; FKHRL1P2; FOXO2; FOXO3A

ORF Size

2022 bp

RefSeq#

NM_001455

Gene Description

FOXO3 belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. FOXO3 likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.

UniGene ID

Hs.220950

HGNC ID

HGNC:3821