mouse PAIP1 shRNA silencing AAV

Cat. No: shAAV-268010

Availability: 4-5 weeks

Name: AAV-m-PAIP1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Paip1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Paip1
Gene Name: polyadenylate binding protein-interacting protein 1
Gene ID: 218693
Gene Synonyms: PAIP-1
ORF Size: 1203 bp
RefSeq#: NM_145457
Gene Description: Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.
UniGene ID: Mm.132584