human INS shRNA silencing Adenovirus

Cat. No: shADV-229744

Availability: 5-8 weeks

Name: Ad-h-INS-shRNA

This is an Adenovirus expressing shRNA for silencing of Human INS.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Knockdown: shRNA screening service available, please inquire about this service or other options.

Species: Human
Gene Symbol: INS
Gene Name: insulin
Gene ID: 3630
Gene Synonyms: IDDM; IDDM1; IDDM2; ILPR; IRDN; MODY10
ORF Size: 333 bp
RefSeq#: NM_000207
Gene Description: After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.
UniGene ID: Hs.
HGNC ID: HGNC:6081