human ING1 shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

ING1

Gene Name

inhibitor of growth family member 1

Gene ID

3621

Gene Synonyms

p24ING1c; p33; p33ING1; p33ING1b; p47; p47ING1a

ORF Size

840 bp

RefSeq#

NM_005537

Gene Description

ING1 encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

UniGene ID

Hs.709738

HGNC ID

HGNC:6062