mouse MVP shRNA silencing AAV

Cat. No: shAAV-265226

Availability: 4-5 weeks

Name: AAV-m-MVP-shRNA

This is an AAV expressing shRNA for silencing of Mouse Mvp.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Mvp
Gene Name: major vault protein
Gene ID: 78388
Gene Synonyms: 2310009M24Rik; LRP; VAULT1
ORF Size: 2586 bp
RefSeq#: NM_080638
Gene Description: Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.
UniGene ID: Mm.228797