human AARS2 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

AARS2

Gene Name

alanyl-tRNA synthetase 2, mitochondrial

Gene ID

57505

Gene Synonyms

AARSL; COXPD8; LKENP; MT-ALARS; MTALARS

ORF Size

2958 bp

RefSeq#

NM_020745

Gene Description

AARS2 belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8.

UniGene ID

Hs.158381

HGNC ID

HGNC:21022