human IFI30 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

IFI30

Gene Name

IFI30, lysosomal thiol reductase

Gene ID

10437

Gene Synonyms

GILT; IFI-30; IP-30; IP30

ORF Size

753 bp

RefSeq#

NM_006332

Gene Description

IFI30 is a lysosomal thiol reductase that at low pH can reduce protein disulfide bonds. The enzyme is expressed constitutively in antigen-presenting cells and induced by gamma-interferon in other cell types. This enzyme has an important role in MHC class II-restricted antigen processing.

UniGene ID

Hs.14623

HGNC ID

HGNC:5398