mouse SLC11A2 shRNA silencing Adenovirus

Product Info

Knockdown

>70% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Slc11a2

Gene Name

solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2

Gene ID

18174

Gene Synonyms

DCT1; DMT1; mk; Nramp2; van

ORF Size

1707 bp

RefSeq#

NM_008732

Gene Description

Important in metal transport, in particular iron. Can also transport manganese, cobalt, cadmium, nickel, vanadium and lead. Involved in apical iron uptake into duodenal enterocytes. Involved in iron transport from acidified endosomes into the cytoplasm of erythroid precursor cells. May play an important role in hepatic iron accumulation and tissue iron distribution.

UniGene ID

Mm.234608