human HSP90B1 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

HSP90B1

Gene Name

heat shock protein 90 beta family member 1

Gene ID

7184

Gene Synonyms

ECGP; GP96; GRP94; HEL-S-125m; HEL35; TRA1

ORF Size

2412 bp

RefSeq#

NM_003299

Gene Description

HSP90B1 encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a microRNA gene located within the 5' exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15.

UniGene ID

Hs.192374

HGNC ID

HGNC:12028