human CENPO shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

CENPO

Gene Name

centromere protein O

Gene ID

79172

Gene Synonyms

CENP-O; ICEN-36; MCM21R

ORF Size

903 bp

RefSeq#

NM_024322

Gene Description

CENPO encodes a component of the interphase centromere complex. The encoded protein is localized to the centromere throughout the cell cycle and is required for bipolar spindle assembly, chromosome segregation and checkpoint signaling during mitosis. Alternatively spliced transcript variants encoding multiple protein isoforms have been observed for this gene.

UniGene ID

Hs.718431

HGNC ID

HGNC:28152