human CNO shRNA silencing Adenovirus

Product Info

Knockdown

>50% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

BLOC1S4

Gene Name

biogenesis of lysosomal organelles complex 1 subunit 4

Gene ID

55330

Gene Synonyms

BCAS4L; BLOS4; CNO

ORF Size

654 bp

RefSeq#

NM_018366

Gene Description

This intronless gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and is a model for Hermansky-Pudlak syndrome. The encoded protein may play a role in intracellular vesicular trafficking.

UniGene ID

Hs.7570

HGNC ID

HGNC:24206