human CPSF3L shRNA silencing Adenovirus

Product Info

Knockdown

>70% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

CPSF3L

Gene Name

cleavage and polyadenylation specific factor 3-like

Gene ID

54973

Gene Synonyms

CPSF73L; INT11; INTS11; RC-68; RC68

ORF Size

1803 bp

RefSeq#

NM_017871

Gene Description

The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex (Baillat et al., 2005 (PubMed 16239144)).(supplied by OMIM, Mar 2008)

UniGene ID

Hs.6449

HGNC ID

HGNC:26052