human TUSC3 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

TUSC3

Gene Name

tumor suppressor candidate 3

Gene ID

7991

Gene Synonyms

D8S1992; M33; MRT22; MRT7; N33; OST3A

ORF Size

1044 bp

RefSeq#

NM_006765

Gene Description

TUSC3 is a candidate tumor suppressor gene. It is located within a homozygously deleted region of a metastatic prostate cancer. The gene is expressed in most nonlymphoid human tissues including prostate, lung, liver, and colon. Expression was also detected in many epithelial tumor cell lines. Two transcript variants encoding distinct isoforms have been identified for this gene.

UniGene ID

Hs.591845

HGNC ID

HGNC:30242