human USP25 shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

USP25

Gene Name

ubiquitin specific peptidase 25

Gene ID

29761

Gene Synonyms

USP21

ORF Size

3168 bp

RefSeq#

NM_013396

Gene Description

Ubiquitin (MIM 191339) is a highly conserved 76-amino acid protein involved in regulation of intracellular protein breakdown, cell cycle regulation, and stress response. Ubiquitin is released from degraded proteins by disassembly of the polyubiquitin chains, which is mediated by ubiquitin-specific proteases (USPs), such as USP25 (Valero et al., 1999 (PubMed 10644437)).(supplied by OMIM, Mar 2008)

UniGene ID

Hs.473370

HGNC ID

HGNC:12624