mouse GGH shRNA silencing AAV

Cat. No: shAAV-260067

Availability: 4-5 weeks

Name: AAV-m-GGH-shRNA

This is an AAV expressing shRNA for silencing of Mouse Ggh.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Ggh
Gene Name: gamma-glutamyl hydrolase
Gene ID: 14590
Gene Synonyms: gamma-GH
ORF Size: 954 bp
RefSeq#: NM_010281
Gene Description: Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates.
UniGene ID: Mm.20461