human JAM2 shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

JAM2

Gene Name

junctional adhesion molecule 2

Gene ID

58494

Gene Synonyms

C21orf43; CD322; JAM-B; JAMB; PRO245; VE-JAM; VEJAM

ORF Size

897 bp

RefSeq#

NM_021219

Gene Description

JAM2 belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. The protein encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript variants have been found for this gene.

UniGene ID

Hs.517227

HGNC ID

HGNC:14686