human PLCD1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-219121
Availability:
3-5 weeks
Name:
AAV-h-PLCD1
This is an AAV expressing Human PLCD1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- PLCD1
- Gene Name
- phospholipase C delta 1
- Gene ID
- 5333
- Gene Synonyms
- NDNC3; PLC-III
- ORF Size
- 2271 bp
- RefSeq#
- BC050382
- Gene Description
- PLCD1 encodes a member of the phospholipase C family. Phospholipase C isozymes play critical roles in intracellular signal transduction by catalyzing the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylglycerol (DAG) and inositol triphosphate (IP3). The encoded protein functions as a tumor suppressor in several types of cancer, and mutations in this gene are a cause of hereditary leukonychia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
- UniGene ID
- Hs.80776
- HGNC ID
- HGNC:9060
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