human FLT3LG shRNA silencing Adenovirus

Product Info

Knockdown

>70% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

FLT3LG

Gene Name

fms related tyrosine kinase 3 ligand

Gene ID

2323

Gene Synonyms

FL; FLT3L

ORF Size

462 bp

RefSeq#

NM_001459

Gene Description

Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 (PubMed 20933441)).(supplied by OMIM, Jan 2011)

UniGene ID

Hs.428

HGNC ID

HGNC:3766