human GSK3B Over-expression AAV

Cat. No: AAV-210586

Availability: 3-5 weeks

Name: AAV-h-GSK3B

This is an AAV expressing Human GSK3B.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: GSK3B
Gene Name: glycogen synthase kinase 3 beta
Gene ID: 2932
ORF Size: 1263 bp
RefSeq#: BC012760
Gene Description: GSK3B is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.593022
HGNC ID: HGNC:4617