human CD244 shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

CD244

Gene Name

CD244 molecule

Gene ID

51744

Gene Synonyms

2B4; NAIL; NKR2B4; Nmrk; SLAMF4

ORF Size

1098 bp

RefSeq#

NM_016382

Gene Description

CD244 encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UniGene ID

Hs.157872

HGNC ID

HGNC:18171