human GIMAP5 shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

GIMAP5

Gene Name

GTPase, IMAP family member 5

Gene ID

55340

Gene Synonyms

HIMAP3; IAN-5; IAN4; IAN4L1; IAN5; IMAP3; IROD

ORF Size

924 bp

RefSeq#

NM_018384

Gene Description

GIMAP5 encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. GIMAP5 encodes an antiapoptotic protein that functions in T-cell survival. Polymorphisms in this gene are associated with systemic lupus erythematosus. Read-through transcription exists between this gene and the neighboring upstream GIMAP1 (GTPase, IMAP family member 1) gene.

UniGene ID

Hs.647079

HGNC ID

HGNC:18005